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For most healthy persons, taking 200 mg of modafinil as directed by a physician is usually regarded as safe. This regular dosage of the popular brand Modvigil 200 is used to treat sleep apnea, narcolepsy, and shift work sleep disorder. The majority of people tolerate this dosage well and report feeling more focused and alert. However, headache, nausea, anxiety, or sleeplessness are possible adverse effects.