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One drug used to treat moderate to severe pain is called Tapentadol. It is a structurally related synthetic opioid analgesic. It is both a norepinephrine reuptake inhibitor and an agonist of the mu-opioid receptor. It blocks norepinephrine from being reabsorbed by attaching to mu-opioid receptors in the brain and spinal cord.

There are two formulations of it available: immediate-release and extended-release. The extended-release formulation should not be used on an as-needed basis; rather, it is intended for continuous pain management.

It is available for purchase from a Genericmedsstore. Genericmedsstore sends Aspadol 150 mg to all 50 USA states and accepts several payment methods.